PRP (Platelet Rich Plasma)

CGF (Concentrated Growth Factors)
What does CGF-CD34 mean?

CGF-CD34 is the name given to the layer containing platelets, leukocytes, and various growth factors and cytokines, obtained by centrifuging a person’s own blood in four different cycles and durations. The stem cells and platelets in the blood, called CD34, secrete growth factors (Growth Hormone) that trigger blood clotting, tissue healing, cell growth, proliferation and rejuvenation, repair of damaged tissues, and natural healing processes.

When any damage occurs in our tissues, our blood collects platelets in that tissue, initiating a repair process. The aim of CGF-CD34 application is to deliver a much larger number of platelets to the target tissue than can be transported through blood circulation, thus enabling the repair of the damaged tissue to begin more quickly and powerfully, and to yield results faster, because the concentration of platelets obtained with CGF-CD34 is 2 to 5 times higher than that in the blood. CGF-CD34 has increasingly been used in the treatment of various diseases in recent years; it is a relatively new and more natural treatment. Although initially used more for “cosmetic and anti-aging” purposes, it has later become an easier method compared to other treatments, especially in musculoskeletal diseases, wound healing, treatment of wounds and burns, and hair loss. There is a great deal of evidence showing that platelet and leukocyte-rich blood fluid – plasma – increases cell proliferation, differentiation, blood supply, and connective tissue – filling between cells, and also activates the defense mechanism against various infections. Thanks to the effect created by the substances produced by platelets, it is used in many areas of medicine and is FDA approved. It is also autologous, meaning it is obtained from the person’s own blood.

HOW IS CGF-CD34 APPLIED?

CGF-CD34 applications are varied;

Skin,
Muscle, tendon, intra-articular,
Body cavities, and
It can be applied to any injured or damaged area.
The injured or damaged area is carefully cleaned. A high concentration of platelet solution and growth factors is injected into the most damaged tissue.
The remaining plasma fluid is injected into less damaged areas. In this way, the body’s regeneration and healing potential is stimulated.

CGF-CD34, besides injection methods, can be applied in:

Mesotherapy,
In a mask,
As a superficial swab,
In combination with energy-based devices,
Mixed into herbal creams and ointments,
As eye drops for dry eyes,
And applied to wounds.

What are the aesthetic applications of CGF-CD34?

• The aging of our skin is caused by the loss of some of its physical properties, just like in the wound healing process. Therefore, in applications aimed at rejuvenating our skin, we actually mimic what our body does when healing a wound using various methods.

• The structure that can repair skin damage most effectively, quickly, and naturally is a part of the whole to which the skin belongs. In CGF-CD34 application, all we do is increase the body’s healing capacity.

• CGF-CD34 for AESTHETIC PURPOSES;

o Face,

o Neck,

o Décolleté,

o Hands,

o Inner thighs – cellulite areas,

o Arms, and all other sagging body areas can be treated.

• IN THE TREATMENT OF SKIN WRINKLES AND SAGGING;

It is successfully applied to:

Wrinkles, sagging, and blemishes on the entire face, including the forehead, eye corners, and nose;

• FOR FACIAL REJUVENATION:

When ozone is added to the CGF-CD34 solution in appropriate doses, it activates platelets, which are healing cells, and significantly increases the amount of Growth Hormone, a healing substance. Oxygen levels in the tissues increase.

• FOR THE TREATMENT OF SKIN SPOTS, PREGNANCY SPOTS, AND SKIN AND ACNE SCARS

• USE OF OZONATED CGF-CD34 FOR AESTHETIC PURPOSES: Especially in facial rejuvenation and hair loss prevention treatments, it forms a very successful combination when used in combination with ozone therapy. Ozone therapy first increases tissue blood flow and oxygen levels. Then, CGF-CD34 therapy promotes tissue healing.

• PROVIDES A LIFTING EFFECT ON THE FACE; Because it promotes rapid skin regeneration, it creates a lifting effect in the treated area.

• PROVIDES A PEELING EFFECT ON THE FACE; After applications like peeling, it promotes rapid skin regeneration. It helps to smooth wrinkles, eliminate depressions, and restore elasticity and radiance. It helps control wounds, cracks, and skin damage that take a long time to heal.

• PROVIDES A FILLING EFFECT ON THE FACE;

It helps to smooth wrinkles, eliminate depressions, and restore elasticity and radiance.

• IN THE TREATMENT OF CELLULITE, STRETCH MARKS CAUSED BY CHILDBIRTH AND WEIGHT LOSS

• IN THE PROTECTION OF HEALTHY HAIR; TREATMENT OF HAIR LOSS

In the treatment of hair loss, it is injected into the areas where hair is falling out, either alone or in conjunction with other treatments. In the treatment of lifeless, dry, thin, and damaged hair, if the hair follicles are alive, it stimulates new hair growth, reduces hair loss, and helps thicken and strengthen the hair. It is a particularly successful treatment for male pattern baldness.

Wrinkles, sagging, and blemishes on the neck and décolleté area;

Wrinkles, sagging, and stretch marks on the upper arms, abdomen, inner thighs, and knees;

Sagging, stretch marks, and scars seen throughout the body.

• OTHER REASONS FOR APPLICATION:

CGF-CD34 applications can be used for aesthetic purposes, such as on genital areas like the vagina and penis, for aesthetic reasons. Ultimately, we can apply it to any area of ​​your body that you feel is showing signs of wear and tear.

WHAT SHOULD BE THE FREQUENCY AND DOSAGE OF CGF-CD34 APPLICATION?

• Scientific studies are insufficient to provide definitive information on this matter. Therefore, the frequency and method of CGF-CD34 application may vary depending on each individual and the response we receive.

• While 3-6 sessions of CGF-CD34 application are generally considered sufficient in practice, additional sessions may be added to the planned number or the treatment may be terminated early. Your doctor should absolutely decide on this.

• There is no risk of overdose with CGF-CD34 application. The amount of blood to be taken from the person is determined according to the amount of plasma containing concentrated platelets sufficient for the area to be treated. This usually means between 10-20 cc of blood for one area of ​​treatment. From this amount of blood, approximately 2-5 cc of plasma containing concentrated platelets is obtained.

HOW LONG DOES THE EFFECT OF CGF-CD34 LAST? WHAT ARE THE SUCCESS RATES?

• CGF-CD34 injection does not involve the application of any drug or product; it only utilizes the body’s own healing potential. Thanks to this healing stimulus, the results are usually slow but permanent.

• Benefits are usually seen after the first injection. A healthy glow appears on the skin a few days after application.

• If the treatment is repeated 3-4 times a year after 3-6 applications every 15-30 or 45-90 days, the effect of the courses is equivalent to a permanent rejuvenating effect.

• The condition of the damaged tissue is re-evaluated 2-4 weeks after the first injection. Additional injections are planned for some cases if needed.

• At the follow-up appointment one year later, depending on the person’s lifestyle:

o If they are in menopause,

o If they smoke or drink alcohol,

o If they do not pay attention to their diet,

o If there is trauma or infection in the area where CGF-CD34 was applied,

o If they cannot protect their skin from sun and ultraviolet rays;

o ADDITIONAL CGF-CD34 TREATMENTS MAY BE NEEDED. IF ADVERSE FACTORS CAN BE AVOIDED, A WAIT OF 1 or 2 YEARS FOR THE SECOND CGF-CD34 TREATMENT.

• While some individuals experience partial improvement, others show complete recovery. Many scientific studies have shown a success rate of 80-85%. Some studies have shown that the healing process continues even 6-9 months after the application. However, as long as the causes of tissue damage are not eliminated, damage can naturally recur.

• A noticeable brightness and lightening of the skin occurs 1 week after the application. Wrinkles soften after the second session. To date, we have not had any clients discontinue treatment due to CGF-CD34 failure or adverse effects.

IS CGF-CD34 AN ALTERNATIVE TO SURGERY?

• No, CGF-CD34 is never an alternative to surgery. However, it is a treatment method that should be applied before surgery.

• If surgery is absolutely necessary, it is possible to reduce the need for surgery and, if surgery is required, to reduce the extent of the surgery by applying CGF-CD34 beforehand.

WHAT ARE THE SIDE EFFECTS OF CGF-CD34 APPLICATION?

• CGF-CD34 treatment has no side effects. Since no pharmacological drugs, products, etc., are administered, and only the patient’s own blood is used, there is no risk of allergy, disease transmission, or tissue incompatibility.

• Of course, bruising, bleeding, redness, burning, and, to a lesser extent, nerve sensitivity causing pain may occur with any injection.

• Since the person’s own blood is given back to them, there is no risk of disease transmission. However, even with strict hygiene measures, unwanted infections can sometimes occur.

• No side effects or adverse events are observed when the procedure is performed with attention to hygiene rules.

• It is a safe procedure because nothing other than the person’s own blood is added to the material used. However, to achieve such a high level of safety, APPROPRIATE KITS MUST BE USED.

• The person can resume their daily life after the treatment.

WHO SHOULD NOT RECEIVE CGF-CD4 TREATMENT?

• Individuals with insufficient platelet count in blood count (hemogram) tests or those who easily bruise or discolor in any area,

• Individuals with active infections,

• Individuals with bleeding disorders or those taking high doses of “blood thinners” on the same day,

• Individuals with chronic liver disease (cirrhosis, hepatitis, etc.),

• Individuals with cancer in the application area, CGF-CD34 is NOT APPLICABLE.

WHAT SHOULD BE CONSIDERED AFTER CGF-CD34 APPLICATION?

• Redness and a feeling of tightness will occur in the area after the application; this will heal spontaneously without the need for treatment. It is recommended not to wash or clean the application area for 4-6 hours.

• It is not recommended to use makeup products for 12-24 hours after CGF-CD34 application.

• Swimming in pools or the sea should be avoided for 12-24 hours after CGF-CD34 application.

• Anti-inflammatory (i.e., rheumatic-pain relievers) medications should not be used after the injection, as they will neutralize the natural healing process stimulated by CGF-CD34. However, if your pain continues due to CGF-CD34 application, you can use pain relievers such as paracetamol or apply a cold/ice compress.

• It is recommended not to apply makeup to the face and neck skin after CGF-CD34 application, and not to use any cosmetic products such as pure ozonized oils or ointments.

• ARE THERE DIFFERENT CGF-CD34 METHODS?

• Yes, depending on the experience of the doctor in the clinic, different CGF-CD34 techniques can be applied, determined according to the individual’s needs.

WHY SHOULD CGF-CD34 BE PREFERRED?

• Because no external chemicals or medications are applied,

• Because it is a natural composition obtained from the person’s own blood,

• Because it has no allergies or side effects,

• Because it is a short-term application,

• Because its effect starts quickly,

• Because its effect is permanent and long-lasting,

• Because the application is easy, practical, and does not require hospital or operating room conditions,

• Because of its effects similar to fillers and mesotherapy, thanks to CGF-CD34, you will get rid of the high bills you pay for cosmetic products for facial wrinkles and hair loss, and you will achieve a much more effective result compared to superficially applied products.

ATTENTION! CGF-CD34 IS A MEDICAL PROCEDURE AND SHOULD ONLY BE ADMINISTERED BY DOCTORS.